This tutorial covers the content and importance of decision-making in economics, the theory of decision-making using mathematical methods in various situations. At the same time, the issues of optimal decision-making in the economy using mathematical programming methods, systematic concessions and decision-making criteria, mathematical models of economic and managerial decision-making, as well as decision-making in conditions of uncertainty based on game theory are described in detail. The textbook covers the theoretical and practical aspects of economic decision-making and is recommended to students of the educational direction “Econometrics” of the bachelor’s degree as a textbook on the discipline “Mathematical methods of decision-making in economics”.